Selank
A nasal peptide based on tuftsin, approved in Russia for anxiety. Research outside Russia is scarce.
- Evidence
- Limited human research
- Half-life
- Minutes
- Sources
- 2 cited
Is selank FDA-approved?
Approved in Russia. Not approved by the FDA. Products sold online as "research chemicals" aren't checked for purity, sterility or dose.
Overview
Selank is a lab-made version of tuftsin, a small immune peptide, with an added tail for stability. In Russia it's used for generalized anxiety. Small Russian trials reported it reduced anxiety and, added to a benzodiazepine, lowered that drug's side effects. Independent studies are lacking.
How it works
Animal studies suggest it affects GABA signaling (the same system benzodiazepines target), serotonin and immune messengers.
How long does selank stay in the body?
Minutes in the blood.
What it's studied for
- Anxiety
- Stress
- Immune effects
Related: Semax, Cerebrolysin, ARA-290 (Cibinetide), Dihexa.
Sources
The studies and prescribing labels this page is written from.
- A comparison of the anxiolytic effect and tolerability of selank and phenazepam. Zh Nevrol Psikhiatr, 2014 PubMed
- Selank Administration Affects the Expression of Genes Involved in GABAergic Neurotransmission. Front Pharmacol, 2016 PubMed